Top 38 Nuclear Energy startups

Updated: Apr 21, 2026
|
Nuclear energy startups are developing new reactor designs, such as small modular reactors, molten salt reactors with enhanced safety, efficiency and waste fuel management.
1
Blue Energy
Country: USA | Funding: $425M
Blue Energy builds nuclear power plants in shipyards because these facilities allow for the processing of large volumes of steel and the easy delivery of it to the construction site after completion. Unlike many nuclear energy startups, Blue Energy isn't developing a new reactor, but rather reimagining the nuclear plant construction process. By shifting the bulk of specialized construction work to the shipyard, Blue Energy significantly reduces project costs. The reactor itself is built in a factory and delivered to the shipyard by barge. While this limits the total number of sites Blue Energy can develop, it can still use rivers to expand into the US, Europe, Africa, and Asia.
2
X-energy
Country: USA | Funding: $1.7B
X-energy produces the Xe-100 - small modular nuclear reactor. It is a fourth-generation, 80-megawatt high-temperature gas-cooled reactor (HTGR), boasting high stability, efficiency, reliability and safety. The reactor can be scaled into 4-pack power plant thanks to its modular design. Its construction maximizes the use of off-the-shelf components, that can be delivered to the site using existing road and rail routes. The reactor does not rely on any active systems, electrical power or human intervention for safety, i.e. it shuts down and dissipates heat passively (as a result of the low power density). X-energy also produces TRISO-X fuel, which can withstand extreme temperatures. X-energy also aims to produce power systems for lunar bases.
3
TerraPower
Country: USA | Funding: $1.5B
TerraPower is developing compact modular nuclear reactors with a closed fuel cycle. Its goal is to make nuclear energy safer and cheaper, while also minimizing radioactive waste. It was co-founded by Bill Gates and partners with GE Hitachi Nuclear Energy. Its sodium-cooled fast reactor, Natrium has capacity up to 345 MW, has a molten salt heat storage system and uses innovative liquid metal cooling. Its advantage is its flexible power output, allowing it to respond to fluctuating demand when combined with renewable energy sources. It uses liquid sodium as a coolant and highly enriched uranium (HALEU) as fuel (although the company is experiencing supply issues). The demonstration reactor project is expected to be operational by 2030.
4
Orano
Country: France | Funding: €900M
Orano offers customers customized solutions for every stage of nuclear energy production: from mining, conversion, enrichment, reprocessing, logistics and engineering to decommissioning and dismantling. The company operates uranium mines in Canada, Kazakhstan and Niger and is one of the world's leading uranium producers. It's offering competitive production costs and advanced recovery technologies. In addition to mining, Orano carries out exploration and development projects in uranium-bearing zones, as well as the rehabilitation and modernization of former mines. Orano is also a world leader in uranium processing, ensuring its customers the efficient, safe and responsible management of spent nuclear fuel. By recovering 96% of recycled materials (95% uranium and 1% plutonium) from spent fuel Orano can reprocess the material and produce new fuel, such as mixed oxide fuel (MOX) for nuclear reactors.
5
Newcleo
Country: UK | Funding: $677.1M
Newcleo develops small modular reactors (SMRs) that uses MOX fuel technology to reprocess spent uranium from conventional nuclear power plants. The 200 MW reactor uses lead as a coolant. This is an ultra-compact module with improved energy density compared to other technologies. MOX fuel, which stands for Mixed Pu-U Oxides consists of depleted uranium (a byproduct of the enrichment process in modern reactors) and plutonium (which is extracted from spent nuclear fuel). The company intends to use already available nuclear material in France in synergy with the in-country environment. Newcleo plans to install the first 30 MW lead-cooled fast reactor (LFR-AS-30) in Savigny-en-Véron and Beaumont-en-Véron.
6
Kairos Power
Country: USA | Funding: $629M
Kairos Power is developing advanced FHR reactor using granular TRI-Structural ISOtropic (TRISO) fuel in pebble form. The technology uses an efficient and flexible steam cycle to convert heat from fission into electricity. Instead of water, used in traditional nuclear reactors, the Kairos Power reactor uses molten fluoride salts as coolant, which has excellent chemical stability and high heat transfer capacity at high temperatures. The reactor requires no electrical power to remove heat from the core after shutdown and there is no need for coolant makeup (since the coolant cannot boil off). The fuel's resistance to extremely high temperatures provides orders of magnitude greater cooling capacity in emergency scenarios compared to water-cooled reactors. The company's goal is to build the Hermes 2 Demonstration Plant (50 MW) by 2030.
7
Valar Atomics
Country: USA | Funding: $599M
Valar Atomics develops small modular nuclear reactors (SMNRs) using proven high-temperature gas reactor (HTGR) technology combined with safe TRISO fuel. HTGRs are optimized to produce high-quality process heat which is used for industrial and chemical applications, providing nearby partners with affordable, abundant and clean energy. Using TRISO-coated fuel particles and helium coolant, the HTGRs passively remove decay heat without active systems or operator intervention. This design minimizes the risk of core damage even in severe accident scenarios. The company plans to mass-produce the reactors and deploy them at so-called gigasites, where they will power AI data centers, industrial facilities, and other customers.
8
Radiant
Country: USA | Funding: $518.8M
Kaleidos produces a portable nuclear microreactor that replaces diesel generators. It is a compact nuclear reactor (1 MW) with all the necessary equipment to generate electricity for remote villages and facilities, as well as backup power for hospitals and data centers. It requires no on-site water consumption thanks to the use of fans for air cooling. Helium conducts heat away from the core and does not become radioactive, eliminating the impact of leaks. Meltdown-resistant TRISO fuel, consisting of uranium particles coated with a ceramic coating, has been used in more than 30 grid-scale reactors since the 1960s. The reactor is assembled and fueled at the factory and delivered by truck or plane. Kaleidos mass-produces microreactors for US military bases.
9
NuScale Power
Country: USA | Funding: $469.6M
NuScale Power has developed small modular reactor NuScale Power Module (NPM) - that was the first to receive design approval from the U.S. Nuclear Regulatory Commission. NPM design is based on proven pressurized water reactor technology and was developed to power power plants, district heating, desalination and industrial hydrogen production. The 77-megawatt reactor weighs 700 tons, allowing it to be shipped from the factory in three sections by truck, rail or barge. NuScale, in partnership with TVA and ENTRA1 Energy, is implementing a pioneering 6-GW SMR program to provide reliable, carbon-free electricity for the future of the seven-state TVA region. The company also established the Energy Research Center - an innovative educational environment offering users hands-on opportunities to apply nuclear science and engineering principles to simulated, real-world nuclear power plant scenarios.
10
Oklo
Country: USA | Funding: $440.6M
Oklo is building a container-sized, continuously operating, carbon-free and emissions-free fission nuclear reactor Aurora. It uses liquid metal coolant and metallic fuel, generates up to 75 MW, features built-in safety and can run on reprocessed waste. The reactor is self-stabilizing, self-regulating and cooled by natural forces. This means the plant is safe for personnel and the technology that enables this has been demonstrated at scale. Oklo also reprocesses nuclear fuel. The company has three project sites and the broadest regulatory support of any modern nuclear power system in the United States. OpenAI co-founder Sam Altman is the primary investor and even served as an early Oklo CEO.
11
Terrestrial Energy
Country: Canada | Funding: $280M
Terrestrial Energy creates Integral Molten Salt Reactor plants that capture the full advantages of molten salt fission technology and the superiority of a molten salt as a reactor coolant.
12
Standard Nuclear
Country: USA | Funding: $186.5M
Standard Nuclear produces TRISO nuclear fuel (from uranium), which is independent of reactor type. The TRISO (TRi-structural ISOtropic) fuel concept was first developed in the 1950s. Poppy-seed-sized uranium particles are coated with ceramic and carbon. They are then packed into larger spheres. This fuel pellet design will be more resistant to meltdown. Standard Nuclear’s modular manufacturing architecture is built for flexibility, allowing us to produce diverse fuel designs on a single production line with minimal switching time and cost. Many nuclear energy startups have announced they will use TRISO in their reactors. The company's clients include Radiant Energy and Nano Nuclear Energy.
13
Last Energy
Country: USA | Funding: $164M
Last Energy builds small modular nuclear reactors that can be mass-produced. The company uses an older 20 MW reactor design developed by the government for a merchant ship. Such reactor is designed to operate without maintenance for its entire service life. It will be delivered to site in an all-metal vessel with a six-year supply of uranium. Heat from fission reactions heats the steel and water flowing through pipes outside uses this heat to spin a steam turbine. At the end of its service life, the steel vessel will serve as a waste container, eliminating the need for separate disposal. The company hopes that this approach, combined with advances in manufacturing, will lead to lower cost of nuclear energy. Last Energy is currently building a 5-megawatt pilot reactor and production of a 20-megawatt commercial reactor is scheduled to begin in 2028.
14
Aalo Atomics
Country: USA | Funding: $136M
Aalo makes small, factory-manufactured nuclear reactors that can fit in your garage, and power anything from a datacenter to a large city.
15
Antares
Country: USA | Funding: $126M
Antares designs and builds microfission reactors for strategic energy applications, including space missions, commercial and military energy resilience. The R1 microreactor can produce from 100 kilowatts to 1 megawatt and uses TRISO fuel, which consists of uranium spheres coated with carbon and ceramics, embedded in graphite. The company performs high-precision machining of the nuclear graphite in-house, speeding design iterations. The optimized reactor design simplifies deployment with a minimal number of actuators. The control drums, made of graphite and boron carbide, have independent actuators, inspired by the designs of historical space reactors. Antares has a manufacturing facility in California and has already tested the first electrically heated demonstration unit (EDU).
16
The Nuclear Company
Country: USA | Funding: $51M
The Nuclear Company is a fleet-scale nuclear development company using proven technology to construct a series of nuclear power plants across America.
17
General Matter
Country: USA | Funding: $50M
General Matter is a nuclear energy company that produces enriched uranium fuel for nuclear energy applications.
18
Thorizon
Country: Netherlands | Funding: €42.5M
Thorizon aims to develop a new generation of nuclear power plants - molten salt reactors.
19
Transmutex
Country: Switzerland | Funding: $43.5M
Transmutex develops technology designed to reduce the stockpile of nuclear waste-based energy.
20
Copenhagen Atomics
Country: Denmark | Funding: $33.6M
Copenhagen Atomics is a manufacturer of thorium reactors.
21
Deep Fission
Country: USA | Funding: $34M
Deep Fission is transforming the energy landscape by installing modular nuclear power reactors a mile deep.
22
Saltfoss
Country: Denmark | Funding: $28.4M
Saltfoss is developing a compact modular reactor based on molten fluoride salt (CMSR), installed on a floating power plant. This power plant can produce up to 800 MW whenever and wherever needed, supporting variable renewable energy generation on windless, cloudy days. In the CMSR, fuel is mixed with molten fluoride salt, which also serves as a coolant. This provides significant safety advantages. Unlike conventional nuclear reactors, the Saltfoss reactor operates at near-atmospheric pressure, eliminating a wide range of accident scenarios. At the end of the 24-year fuel cycle, the fuel is returned to the supplier, where the short-lived fission products are separated and stored.
23
Phoenix
Country: USA | Funding: $26.6M
Phoenix designs and manufactures the highest-yielding neutron generators and commercializes nuclear technologies for practical applications.
24
Hexana
Country: France | Funding: €25M
Hexana intends to develop an AMR based on the sodium-cooled fast reactor technology that incorporates a high-temperature storage device.
25
Clean Core Thorium Energy
Country: USA | Funding: $18.1M
Clean Core Thorium Energy develops advanced nuclear fuel for existing reactors.
26
NuCube Energy
Country: USA | Funding: $13M
NuCube Energy is developing a high-temperature modular microreactor designed to generate electricity and industrial heat at temperatures up to 1100 degrees Celsius. The company's architecture is designed with simplicity, security and supply chain efficiency in mind, enabling scalable deployment across industrial facilities and remote data centers. The reactor design contains no moving parts and, unlike many competing microreactor concepts, utilizes the generated heat for industrial heating. Currently, the company is conducting materials testing, finalizing the design configuration, and collaborating with regulatory agencies to advance to demonstration and commercial implementation.
27
Nuclearn
Country: USA | Funding: $13M
Nuclearn is a software company delivering AI solutions for automating Nuclear Industry tasks.
28
Blykalla
Country: Sweden | Funding: SEK80M
Blykalla is developing and building small modular reactors to deliver the next generation of clean energy. We take leading research to industrialization through our Swedish Advanced Lead Reactor (SEALER).
29
Atomic Canyon
Country: USA | Funding: $7M
Atomic Canyon uses artificial intelligence to improve efficiency and optmize operations of nuclear power plants. The company is developing Neutron, an AI search engine for searching billions of pages of nuclear documentation. Using the Nuclear Regulatory Commission (NRC) database and the world's fastest supercomputer at Oak Ridge National Laboratory (ORNL), it understands and processes nuclear terminology with unprecedented accuracy, interpreting complex documents to let executives make more informed data-driven decisions. Neutron is based on open-source AI model FERMI intended for sentence vector representations, specifically designed for nuclear data. Atomic Canyon is working in partnership with PG&E's Diablo Canyon power plant, the only remaining nuclear power plant in California.
30
Blue Wave AI Labs
Country: USA | Funding: $6.9M
Blue Wave AI Labs is using predictive analytics to operate nuclear reactors across the United States and to help them operate as safely and efficiently as possible
31
Transatomic Power
Country: USA | Funding: $5.5M
Transatomic Power is a nuclear reactor design company offering a waste-annihilating molten salt reactor.
32
Hylenr
Country: India | Funding: $3M
LENR technology offers a promising alternative for power generation by amplifying input electricity to produce heat for steam generation. It strives to be the global leader in Low Energy Nuclear Reactor (LENR)
33
First American Nuclear
Country: USA | Funding: $2.5M
FANCO was founded by a team of nuclear energy veterans led by Bill Stokes, who have implemented some of the most advanced nuclear projects in US history. Their expertise is the foundation of FANCO and sets it apart from startups chasing unproven ideas. Their 240 MW EAGL-1 reactor is a modular and reliable reactor based on proven low-pressure fast reactor technology, optimized for modern energy needs. It uses safe and environmentally friendly lead-bismuth coolant and operates in the fast neutron spectrum, extracting more energy from fuel and reducing waste for a cleaner future. The EAGL-1's optimized design eliminates the need for expensive intermediate systems and containment vessels, reduces mechanical complexity, and improves overall system reliability. That means the potential for faster deployment and dramatically lower front-end fuel cycle costs. FANCO plans to build its own Nuclear Plant Powered by Its Own Waste in Indiana.
34
Deep Space Energy
Country: Latvia | Funding: €450K
Deep Space Energy is developing a new radioactive generator technology for the European space and defense industry, which will ultimately power lunar exploration. DSE's generators use radioisotopes - materials derived from nuclear waste - to generate heat through natural decay. The solution converts this heat into electrical energy, requiring five times less radioisotope fuel than thermoelectric generators currently used in space. The generator is used to back up satellite power systems, providing backup power independent of solar energy, making it critical for important military reconnaissance assets. The work is funded by government contracts and grants from the European Space Agency, NATO's DIANA program, and the Latvian government.
35
Atomic Alchemy
Country: USA | Funding: $150K
Atomic Alchemy is to become the world’s most reliable supplier of radioisotopes for medical, research, exploration, and industrial use
36
Stellaria
Country: France
Stellaria is looking to develop an energy system based on the molten chloride fast reactor (MCFR) technology.
37
Elysium Industries
Country: USA
Elysium Industries develops molten chloride salt fast reactors. This reactor is capable of providing base-load and clean power while addressing the current issues in the nuclear power industry.
38
Indigo Nuclear
Country: USA
Indigo Nuclear is focused on creating an "express lane" for companies to add nuclear to their energy portfolios. The company provides staffing and operations of Small Modular Reactors for Data Centers, providing an effective outsourcing solution.
  See also:
Alexander Gillet
Editor: Alexander Gillet
Alexander Gillet is a senior editor for EnergyStartups. He has a deep background in energy sector and startups. Alexander graduated from Emlyon Business School, a leading French business school specialized in entrepreneurship. He has helped several non-profit organizations dedicated to promoting environmental education and sustainability and has written over 250 articles on energy technology for various websites. In his free time, Alexander enjoys yoga, camping and exploring the Blue Ridge Mountains. You can contact Alexander at alexgillet(at)energystartups(dot)com